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Featured Articles
All articlesL-Theanine and Mood: What the 2026 Meta-Analysis of 31 Trials Found
A new systematic review and meta-analysis in Molecular Psychiatry pools 31 randomised trials of L-theanine. Here is what it found on attention, stress, and depressive symptoms, and where the evidence is still thin.
Vitamin D and Cognition: What the VitaMIND Trial Found
A 620-person, 24-month randomised trial tested whether correcting mild to moderate vitamin D deficiency improves cognition in older adults. It found no benefit on any measure, cognitive, functional, or wellbeing.
High-Dose DHA and Cognition: The 2026 Target-Engagement Trial
A 2026 randomised trial gave older adults at dementia risk 2g/day DHA for two years and confirmed the omega-3 reached the brain in force. Cognition and hippocampal volume were unchanged versus placebo.
Latest Research
View allGlucosamine and Alzheimer's Disease: What the New Hyperglycosylation Research Shows
A June 2026 Nature Metabolism study found oral glucosamine worsened cognition in Alzheimer's mouse models and was linked to faster progression in a large retrospective human cohort. Here's what the mechanism and the data actually show.
Huperzine A: Cognitive Evidence and the Trial Quality Problem
Huperzine A is a potent plant-derived acetylcholinesterase inhibitor. A research review of its mechanism and the tension between decades of positive Chinese trials and one rigorous negative US trial.
Creatine and Cognitive Function: The Meta-Analysis Flaw Behind the Popular Claim
A widely cited 2024 meta-analysis said creatine improves memory and processing speed. EFSA rejected the health claim, and a 2026 commentary explains the statistical error behind it.
Ashwagandha and Liver Injury: The Case Reports Behind the TGA Safety Signal
Australia's TGA updated its ashwagandha safety advisory in July 2026. Here's what the underlying case reports, LiverTox data, and causality assessments actually show.
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4Neuroscience is an independent research hub synthesising peer-reviewed studies on nootropic peptides, cognitive neuroscience, and human performance, written for researchers, students, and health-conscious Australians.